Abstracts

My lab members are italicized, * indicates equal contribution

Chen, P-L, Gaston D, Orr A., Dyack S, McMaster CR, Gardner M, and Bedard K. (2015) Induced pluripotent stem cell technology as a tool to study Arrhythmogenic Right Ventricular Cardiomyopathy in a Maritime family. International Society of Stem Cell Research 2015, Stockholm, Sweden: June 24-27, 2015. (abstract accepted)

Chen, P-L, Gaston D, Orr A., Dyack S, McMaster CR, Gardner M, and Bedard K. (2015) Induced pluripotent stem cell technology as a tool to study Arrhythmogenic Right Ventricular Cardiomyopathy in a Maritime family. European Society of Human Genetics 2015, Glasgow, Scotland, UK: June 6-9,  2015. (abstract accepted)

Lamoureux E, Whitehouse S, Gaston D, Majewski J, Brown A, LeBlanc M,  Foulkes W, McMaster CR, Fernandez C, Bedard K.  Analysis of Gene Promoter Methylation in Familial Wilms Tumour.  Pathology Research Days, 2014.

Brown A, LeBlanc MA, Gaston D, Majewski J, Foulkes W, Fernandez CV, McMaster CR, Bedard K.  Epigenetic Mechanisms Potentially Influencing Gene Expression in a Rare Form of Familial WIlms Tumour.  European Society of Human Genetics, Milan, Italy, May 2014.

Brown A, LeBlanc MA, Gaston D, Majewski J, Foulkes W, Fernandez CV, McMaster CR, Bedard K.  Epigenetic Mechanisms Potentially Influencing Gene Expression in a Rare Form of Familial WIlms Tumour.  Pathology Research Days, 2014.

Mackley MP, Nightingale N, Huang WY, Bedard K. A Quantitative Approach: Developing A Protocol To Measure mRNA Level Of Oncogenic BRAFV600E In Different Tumours By qRT-PCR. Jackson Laboratories 55th Annual Shortcourse on Mammaliam  and Medical Genetics, 2014.

Mackley MP, Nightingale N, Huang WY, Bedard K. A Quantitative Approach: Developing A Protocol To Measure mRNA Level Of Oncogenic Brafv600e In Different Tumours By qRT-PCR. Pathology Research Days, 2014.

Robinson CA, Yorke J, Corkery D, Dellaire G, McMaster CR, Bedard K. Functional analysis of HYOU1 and its role in Cape Breton Renal Failure. Pathology Research Days, 2014.

Chen PL, Orr A, McMaster CR, Bedard K.  Inducible Pluripotent Stem Cell Technology as a Tool to Study Arrhythmogenic Right Ventricular Cardiomyopathy in a Maritime Family.  Pathology Research Days, 2014.

Gaston D, Whitehouse S, M Nightingale,  MacGillivray C, Orr A, Steele P, Rideout AL, Huang WY,  Greer W, Majewski J, Dyack S,  Ludman M, Penney LS,  Fernandez CV,  McMaster CR ,  Bedard K.  Mutations in MAP3K6 are Associated with Familial Gastric Cancer.  Pathology Research Days, 2014

Gaston D,* Hansford S,* Oliveira C, Nightingale M, Pinheiro H, Macgillivray C, Kaurah P, Rideout AL, Steele P, Soares G, Huang WY, Whitehouse S, Blowers S, LeBlanc MA, Jiang H, Greer W, Samuels ME, Andrew A, Fernandez CV, Majewski J, Ludman M, Dyack S, Penney LS, McMaster CR, Huntsman D, Bedard K.   Germline Mutations in MAP3K6 Predispose to Gastric Cancer.  European Society of Human Genetics, Milan, Italy, May 2014  (selected for oral presentation)

Robitaille J, Dyack S, Gaston D, Chen L, Whitehouse S, Roslin N, Nightingale M, Gillett R, Patterson I, Macgillivray C, Bramwell L, Majewski J, Orr A, McMaster CR*, Bedard K*. A mutation in DST is present in individuals with congenital alacrima. 2014 Canadian Ophthalmological Society, Halifax NS.

Robitaille J, Gillet R, Leblanc M, Gaston D, Nightingale M, Mackley M, Parkash S, Hathaway J, Traboulsi E, Ells A, Heon E, Roy M, Shalev S, MacGillivray C, Wallace K, McMaster C, Bedard K. Phenotypic overlap between familial exudative vitreoretinopathy (FEVR) and microcephaly lymphedema chorioretinal dysplasia (MLCRD) caused by KIF11 mutations. 2014 Canadian Ophthalmological Society, Halifax NS.

*Mackley MP, Huang WY, Bedard K. A quantitative approach: developing a protocol to measure mRNA level of oncogenic BRAFV600E in tumour samples by qRT-PCR. 2014 Cameron Conference. Dalhousie University, Halifax NS. (*selected for oral presentation)

Bentley VL, Veinotte C, Corkery D, LeBlanc M, Bedard K, Weng AP, Dellaire G, Berman JB. Zebrafish Xenotransplantation: A Preclinical Therapeutic Model for T-cell Acute Lymphoblastic Leukemia. 2013 American Society of Hematology, New Orleans.

LeBlanc MA, Penney LS, Gaston D, Shi Y, Aberg E, Nightingale M, Jiang H, Gillett R, Fahiminiya S, MacGillivray C, Wood EP, Acott PD, Khan MN, Samuels ME, Majewski J, Orr A, McMaster CR, Bedard K. A rearrangement in OCLN causes brain calcification and renal dysfunction. 2013 European Society of Human Genetics Conference, Paris, France.

Robinson C, Casey MA, Bedard K. Cutis Laxa Type II: A role for PYCR1 in survival after cellular stress. 2013 Pathology Research Days, Dalhousie University.

Gaston D, Fernandez CV, McMaster CR, Bedard K. Pitfalls and Populations: The importance of population genetics, data visualization, and pluralistic analysis methods to next-generation sequencing data for human disease genetics. 2013 Pathology Research Day, Dalhousie University, Halifax NS.

*LeBlanc MA, Penney LS, Gaston D, Shi Y, Aberg E, Nightingale N, Fahiminiya S, Majewski J, McMaster CR, Bedard K A rearrangement in OCLN causes brain calcification and renal dysfunction. 2013 Pathology Research Day, Dalhousie University, Halifax NS. (*winner of first place for oral presentation)

*LeBlanc MA, Nightingale M, Gaston D, Hamel N, Zhang, J, Lalonde E, Majewski J, Foulkes W, Orr A, Fernandez CV, McMaster CR, Bedard K. Identification of the genomic mutation causing a rare inherited form of kidney cancer. Beatrice Hunter Cancer Research Institute poster session Halifax, November 2012. (* winner first place poster session)

Whitehouse SD, Bedard K. Evaluation of Celastrol and Resveratrol as Antioxidants and Inhibitors of ROS Generation. 2012 NOX Gordon Conference.

Whitehouse SD, Bedard K. Evaluation of Celastrol and Resveratrol as Antioxidants and Inhibitors of ROS Generation. 2012 Pathology Research Day, Dalhousie University, Halifax NS.

Casey MA, Robinson C, McMaster C, Bedard K. Cellular resistance in a model of Cutis Laxa type II. 2012 Pathology Research Day, Dalhousie University, Halifax NS.

Chen PL, Greer W, Fernandez CV, McMaster CR, Bedard K. Development of a cell culture model for the Charcot-Marie-Tooth disease – a functional study of the LRSAM1 protein. 2012 Pathology Research Day, Dalhousie University, Halifax NS.

*Gaston D, Orr A, Fernandez CV, McMaster CR, Bedard K. Next-Gen Sequencing, Systems Biology, and the Data Deluge: Identifying Causative Genes of Rare Diseases in the Post-Genomics Era. 2012 Pathology Research Day, Dalhousie University, Halifax NS. (* selected for oral presentation)

LeBlanc MA, Nightingale M, Gaston D, Majewski J, Orr A, Fernandez CV, McMaster CR, Bedard K. Identification of the genomic mutation causing a rare inherited form of kidney cancer. 2012 Pathology Research Day, Dalhousie University, Halifax NS.

Nightingale M, Osborne N, Orr A, Bedard K, Riddell C. Carrier screening in the Acadian population of the Maritime Provinces using MLPA. 2012 Pathology Research Day, Dalhousie University, Halifax NS.

Whitehouse S and Bedard K. The effect of p22 polymorphisms on reactive oxygen species formation by NOX1. 2011 Club Oxydase, Grenoble France.

Whitehouse S and K Bedard K. The effect of p22 polymorphisms on reactive oxygen species formation by NOX1. 2011 Pathology Research Day, Dalhousie University, Halifax NS.

Black C and Bedard K. The Effect of a Novel PYCR1 Mutation on Protein Function and ROS Metabolism. 2010 Health Research Trainee Day, Halifax NS.

Whitehouse S and Bedard K. Genetic Factors in Reactive Oxygen Species Production. 2010 Pathology Research Day, Dalhousie University, Halifax NS.